[3] Players control a United States Air Force pilot who was taken as a prisoner of war in Vietnam in 1972.

[4] The Sega Genesis version is single-player only, as the player now controls Captain Addis of the United States Army, who must rescue his fellow soldiers twenty years after he failed to retrieve his men during the Vietnam War.

He must now re-navigate through the Ho Chi Minh trail in order to liberate his captured comrades-in-arms.

An option menu allows players to choose from either an easy, normal, or hard difficulty level in addition to the number of initial lives.

[6] In Japan, Game Machine listed Caliber .50 on their December 15, 1989 issue as being the second most-successful table arcade unit of the month.