The third season began with a small pre-season on February 1, 2010 and consisted on competing teams for money.
At the end of this pre-season all the money raised so far was donated to the victims of the earthquake of February 27 that affected Chile.
The new season of Calle 7 started on March 15, 2010, with new players and game mode in couples.
Like a previous seasons the nominees were chosen every day according to the team that lost, in this case the couple.
The grand finale was on June 5 and the winners were the winner of Pelotón Francisco "Pancho" Rodríguez and Maite Orsini, winning 6 million Chilean pesos, the second place was Federico Koch and Camila Nash winning 1 million Chilean pesos.