The calle de la Princesa is a street in Madrid, Spain.

The street, starting at the Plaza de España sort of is a North-West prolongation of the Gran Vía.

[3] Formerly known as "Duque de Liria", the street was renamed as Princesa ("Princess") in 1865, after Isabella de Borbón y Borbón (popularly known as "La Chata"), first-born daughter of Queen Isabella II.

[3] Despite the impending urbanisation of the neighborhood of Argüelles, during the Sexenio Democrático the works of the leveling to link the streets of Leganitos and Duque de Osuna and Princesa were halted.

[6] A sculpture of Agustín Argüelles was inaugurated at the junction of Princesa with Marqués de Urquijo in 1902.