Just facing the UPRM's Barcelona Gate is a junction where merges the Avenida Alfonso Valdés Cobián and Pedro Albizu Campos Avenue aside with the Parque de los Próceres.
In this point the road runs over a 6-lane bridge over the Yagüez River going southbound to Barcelona Sector, where some fast foods, a gas station, shops and pubs like the legendary El Garabato are located.
Across the Méndez Vigo, Candelaria, Ernesto Ramos Antonini, Santiago R. Palmer and Luis Muñoz Rivera streets is the busiest commercial zone of the Mayagüez city center.
Next is placed the entrance to Río Cristal clusters, and forward are placed the Escuela Superior José De Diego (now a closed high school building) and the Pontifical Catholic University of Puerto Rico at Mayagüez.
This street was named by disposition of the Municipal Legislative as a homage to the independence advocate and abolitionist leader Dr. Ramón Emeterio Betances.