Austrocallerya megasperma is a woody climber with stems up to 20 m (66 ft) long covered with flaky bark.

[2][3] This species was first formally described in 1858 by Ferdinand von Mueller who gave it the name Wisteria megasperma in his Fragmenta Phytographiae Australiae from specimens he collected with Walter Hill near the Pine River.

[4][5] In 1994, Anne M. Schot moved the species to Callerya as Callerya megasperma in the journal Blumea[6] and in 2019, James A. Compton and Brian David Schrire moved it to their new genus Austrocallerya as Austrocallerya megasperma, based on the plant's morphology, and nuclear and chloroplast DNA sequences.

[2] This vine is a valuable indicator species as it often grows in association with the birdwing butterfly vine (Aristolochia praevenosa), one of the only food plants for the caterpillars of the rare Richmond birdwing butterfly (Ornithoptera richmondia).

[8] Austrocallerya megasperma itself is a food plant for the caterpillars of the pencilled blue (Candalides absimilis) and narrow-banded awl (Hasora khoda) butterflies.