[4] Past guests on The Callie Crossley Show include filmmaker Errol Morris, historian Howard Zinn, authors Junot Díaz, Frank Bruni, Edwidge Danticat, Colson Whitehead, Isabel Wilkerson, David Remnick, lawyer/author Charles Ogletree, actors Rachel Dratch, Leonard Nimoy, Anna Deavere Smith, and Wayne Brady, choreographer Bill T. Jones, and many more.

Crossley is a regular contributor on Public Radio International's The Takeaway, and has guest hosted NPR's Tell Me More with Michel Martin, for which she also contributes commentary about wine.

She is an occasional commentator on CNN's Reliable Sources,[6] and appears regularly on Fox Morning News WXFT-TV.

[8] Crossley produced two of the six hours in the 1987 television documentary series Eyes on the Prize, Show Four--"No Easy Walk" and Show 6--"Bridge to Freedom", which was nominated for an Academy Award for Best Documentary Feature in 1988 during the 60th Academy Awards.

[11] She is a featured speaker on Forum Network, a public media service of PBS, NPR and Corporation for Public Broadcasting providing a free online video lecture series featuring the world's leading scientists, educators, artists and authors Forum Network.