Dr. Leonard Gillespie, the crusty senior diagnostician at New York's Blair General Hospital, has a severe disagreement with a pupil, intern James Kildare, over a suspected case of Q fever.

On the day that Kildare begins his new job, young Red enters the dispensary and confidentially asks the intern to help an injured friend, Nick Lewett.

Against hospital procedure and the law requiring reporting of all gunshots to the police, Kildare continues to treat Nick in the hideout, even after he knows that the boy is wanted for the murder of bookmaker "Footsy" Garson over a gambling debt.

A worried Gillespie arranges with Kildare's mother to call him home to help his physician father with a difficult patient, but when the intern returns, he is picked up by the police along with Nick.

[1] New York Times reviewer Frank Nugent, while bemoaning the damage done to artistic values by series pictures, still called it "pleasantly entertaining" and "on the whole, successfully sugar-coated".