Worthy has guest-starred in numerous television series, including ABC Family's Kyle XY, The CW's Supernatural and Smallville, CTV's Flashpoint, The Hub's R. L. Stine's The Haunting Hour: The Series, Disney Channel's Good Luck Charlie, Disney XD's Zeke and Luther, and Two and a Half Men.

[1][2] He made his screen debut at the age of 9, guest-starring in Fox's Night Visions (directed by Bill Pullman).

In 2013, he created, wrote, and executive produced—along with Derek Baynham and Kelly May—the sketch comedy series The Coppertop Flop Show, which was picked up by Disney Channel to air in late 2013.

[8] In July 2017 Worthy was cast as Robbie Baldwin / Speedball in Freeform's upcoming New Warriors television series.

[12] In February 2021, it was announced that Worthy had been cast as Jasper in the upcoming Netflix thriller series Pieces of Her, which is adapted from the Karin Slaughter novel of the same name.