Calvin Hastings Plimpton (7 October 1918 – 30 January 2007) was an American physician and educator, who served as president of Amherst College and American University of Beirut.

He is known for appointing a commission in 1970 whose findings resulted in the admission of women to Amherst in 1975.

Plimpton attended Phillips Exeter Academy and received a bachelor's degree from Amherst, where he was a member of Delta Kappa Epsilon fraternity.

He served in the U.S. Army as a captain during World War II.

John William Ward was his successor at Amherst College.