At an early age, he (left-handed) and his identical "mirror-image" twin brother Tyler (right-handed) demonstrated a pattern of teamwork, building Lego together and playing musical instruments.

[8][9] On June 14, 2002, Winklevoss's older sister, Amanda, died from cardiac arrest induced by drug overdose.

[10] He enrolled at Harvard University in 2000 for his undergraduate studies where he majored in economics, earning an AB degree and graduating in 2004.

[15] The three conceived of a social network for Harvard students named HarvardConnection; the concept ultimately expanded to other schools around the country.

In January 2003, they enlisted the help of fellow Harvard student, programmer and friend Sanjay Mavinkurve to begin building HarvardConnection.

Gao, a senior in Mather House, opted not to become a partner in the venture, instead agreeing to be paid in a work for hire capacity.

The suit alleged that Zuckerberg had copied their idea[16][17] and illegally used source code intended for the website he was hired to create.

[18][19][20][21] Facebook countersued in regard to Social Butterfly, a project put out by The Winklevoss Chang Group, an alleged partnership between ConnectU and i2hub, another campus service.

The Winklevosses had argued that the court lacked jurisdiction because the settlement with Facebook has not been distributed and therefore Chang has not suffered any injury.

Chang alleges that he has received nothing in return for the substantial benefits he provided to ConnectU, including the value of his work, as well as i2hub's users and goodwill."

The court concludes that Chang has pled sufficient facts to confer standing with respect to his claims against the Winklevoss defendants.

[48] Winklevoss rowed at Harvard University for four years under coach Harry Parker, while completing his undergraduate studies.

[49] As a Harvard Crimson in 2004, he helped the "God Squad" win the Eastern Sprints, the Intercollegiate Rowing Association Championship, and the Harvard–Yale Regatta as part of an undefeated collegiate racing season.

They defeated the 2004 British and French Olympic eight boats in the semi-final to earn a spot in the grand final, in which they placed 6th.

[57] He rowed with his brother in the men's coxless pair event that took place at the Shunyi Olympic Rowing-Canoeing Park.

[58] In 2009, Winklevoss won a bronze medal at the Rowing World Cup in Lucerne, Switzerland, in the men's coxless four event.

Cameron and his brother Tyler are both played by actor Armie Hammer in The Social Network (2010), a film directed by David Fincher about the founding of Facebook.

[60] Cameron and Tyler are featured as the main protagonists in the 2019 book Bitcoin Billionaires: A True Story of Genius, Betrayal, and Redemption.