There are several theories about the origin of Campaspero's name, a leading one being from the Spanish phrase "Rough Field," which correctly describes the rocky terrain of the area.

This building dates back to the 18th century, when it was decided to raise this temple due to the condition of ruin of the previous one, which is missing today.

The church has a simple structure, and keeps within some carvings of notable interest, as that of the Ascension, made by Pedro Berrugete, a sculptor from the neighbour town of Peñafiel, in the second half of the 18th century.

The images of Santo Domingo of Guzmán (the church's patron saint) and San Buenaventura were carved in the same century.

They also share the Baroque style, and were carved in wood for Pedro Ventosa, an artist from Sepúlveda (Segovia).