The program adopted the name Campbell Brown: No Bias, No Bull shortly before Election Day 2008.
A segment at the end of the broadcast called "Dear Mr. President" featured young kids who wrote letters to Barack Obama, and would like him to read them.
Along with a revamped opening, the show adopted a 4-person panel set-up, something initially launched in May 2009 when Roland Martin filled in for Brown while she delivered her second child.
In June 2010, CNN announced that a new program entitled Parker Spitzer, hosted by former New York governor Eliot Spitzer and conservative columnist Kathleen Parker, would be replacing Campbell Brown later in the year.
CNN's Campbell Brown has attracted audiences which put it well behind its competitors in the 8 pm time slot, including Fox News's O'Reilly Factor, MSNBC's Countdown with Keith Olbermann, and HLN's Nancy Grace.