Campochiaro is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about 20 kilometres (12 mi) southwest of Campobasso.

Campochiaro borders the following municipalities: Castello del Matese, Colle d'Anchise, Guardiaregia, Piedimonte Matese, San Gregorio Matese, San Polo Matese, Vinchiaturo.

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