Campolieto is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about 11 kilometres (7 mi) northeast of Campobasso.

Campolieto borders the following municipalities: Castellino del Biferno, Matrice, Monacilioni, Morrone del Sannio, Ripabottoni, San Giovanni in Galdo.

Campolieto is twinned with:

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