"Can't Let Go" is a song written by American singer-songwriter Randy Weeks, made famous by Lucinda Williams in 1998–1999.

The Boot described Williams's version of "Can't Let Go" as "a Texas roadhouse barn-burner, with charred licks and vocals that convey equal parts anguish and defiance."

[8] After Williams made the song famous, Weeks included his own version of it on his 2000 album Madeline, with backing vocals by Manny Gonzalez.

[9] In November 2021, English rock singer Robert Plant (ex–Led Zeppelin) and American bluegrass violinist/vocalist Alison Krauss released their second collaborative album, Raise the Roof.

[10] By December 1, the single had amassed 327,000 U.S. streams, 262,000 radio audience impressions and 2,500 downloads sold, entering the Hot Rock & Alternative Songs chart at number 39 for one week.

Reviewing "Can't Let Go", NPR praised the harmonies of Plant and Krauss, and called out the "shuffling grooves of drummer Jay Bellerose.

"[12] Stereogum described the song as "an eminently likable bluesy shuffle built around a guitar part that will burrow its way into your brain.