The Canadian Screen Award for Best Lead Performance in a Drama Series is an annual award, presented by the Academy of Canadian Cinema and Television as part of the Canadian Screen Awards program, to honour the best leading performance in a Canadian television comedy series.
It is a merger of the former awards for Best Actor in a Drama Series and Best Actress in a Drama Series, following the academy's announcement in August 2022 that it would start presenting gender-neutral acting awards instead of gendered ones.
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