The Cannobino is a little river or stream located in the province of Verbano Cusio Ossola in the region of Piedmont in the north of Italy, which by the local population often is simply called 'Il Fiume' (the river).

The first 20 kilometres (12 mi) of the stream is not wider than some 10 metres (33 ft), but next to the church of Sant'Anna in the villages of Traffiume the water flows through a cleft that is many meters deep and ends up in a natural basin a few meters deep and almost 100-metre (330 ft) wide.

On this journey, approximately 25 kilometres (16 mi) long, the river crosses the following municipalities: Malesco, Gurro, Valle Cannobina and finally Cannobio.

In general the Cannobino is a quietly flowing stream, but a couple of times a year the influx of water from the surrounding mountains suddenly increases strongly, causing the stream to change into a wild watermass.

A number of campgrounds and hotels are situated on its banks and near the Sant'Anna cleft the stream is wide and deep enough for diving, swimming and sailing rubber boats.