It is located at the start of the Los Angeles River, and adjacent to Topanga Canyon Boulevard to the west and Owensmouth Avenue to the east.

[citation needed] The high school's buildings were in the Beaux-Arts Neoclassical architectural style, unusual for a small town two years old.

[citation needed] The Assembly Hall was built during the Great Depression by the Federal Emergency Administration of Public Works and completed in 1939.

The CAM Magnet has sequential courses designed to promote careers in digital media and arts, communication technology, and programming and coding.

The EEVS Magnet has sequential courses designed to promote careers in engineering, architecture, green technology, veterinary science, agriculture and sustainable farming, social ecology, building trades engineering, veterinary and environmental science.

Canoga Park High School fields teams for boys and girls in football, basketball, soccer, baseball, softball, volleyball, tennis, golf, track & field, cross country, water polo, swimming and wrestling.

The teams have won CIF Championships in sports, including football, basketball, baseball, track & field, soccer, volleyball, cross country and tennis.