The match, usually played in January at the Mardyke Sports Ground, is often regarded as a pre-season warm-up game for the two participants.
Organised by the Cork County Board, admission to the match is free; however, those attending the game are asked to make a donation to volunteer collectors on the day, with all proceeds going to the Irish Alzheimer's Society.
The Canon O'Brien Cup was launched in 2013 by GAA President Liam O'Neill.
Canon Michael O'Brien, who was heavily involved as a coach with both teams, led UCC to eight consecutive Fitzgibbon Cup titles between 1981 and 1988 and led Cork to the 1990 All-Ireland title.
It was presented to Canon O'Brien in 1983 by the UCC hurling squad after he had helped them to win three Fitzgibbon Cup titles in-a-row.