Canonsburg is a borough in Washington County, Pennsylvania, United States, 18 miles (29 km) southwest of Pittsburgh.

It is adjacent to the Southpointe office park located in Cecil Township, which has a number of large corporate tenants.

Yenko Chevrolet, one of largest and most notable custom muscle car shops of the late-1960s and early-1970s, was also located in Canonsburg.

In the television series Supernatural, the town is featured in the episode "Monster Movie", which is set in the borough during the Oktoberfest celebration.

The notes of the first session of the Washington County Court during that year indicate a call for a road from Canon's mill to Pittsburgh.

The road to Pittsburgh, called Pitt Street, remains in part today as an archaic and indirect route to the city.

Many of the participants in the Whiskey Rebellion in July 1794 were residents of present-day Washington County, which includes Canonsburg.

Canonsburg's largest financial draw having left, it would take the introduction of the railroad system to return the city to its former glory.

The railroad system, on its way from Mansfield (Carnegie) to Washington (See: Chartiers Branch), was fully operational, as scheduled, on May 18, 1871.

The first scheduled train departed from the Washington depot carrying "borough authorities, the committee of arrangement and reception, as well as Rankin’s Cornet Band and a number of…prominent citizens who had been invited to join the excursion."

The special had 12 coaches pulled by two locomotives and was filled with a large number of dignitaries, most especially the mayors of Pittsburgh and Allegheny.

The special then made it down the newly laid tracks, passing stations full of spectators to cheer on the train.

Canonsburg had a large crowd of supporters, and many people climbed aboard the train to ride along to Washington.

There, led by Pittsburgh's Great Western Band, the crowd marched to Town Hall for a round of speeches.

[9] The Canonsburg Armory, Hawthorne School and Roberts House are listed on the National Register of Historic Places.

From 1930 to 1942, the company purified uranium ore. Marie Curie was invited to the United States in 1921 and was given an honorary degree by the University of Pittsburgh, and one gram of radium.

Residual radioactivity was consolidated into a covered, clay-lined cell at the Canonsburg mill site, which is fenced and posted.

[6][17] The parade starts on Morganza Road and runs down the length of Pike Street, heading westward, for approximately 1.5 miles.

Parade members include high school and other marching bands from Washington County and the surrounding areas, local sports teams and cheerleaders of all ages, fire trucks, emergency responders, shriners, unicyclists, jugglers, pipers, polka bands, various church groups, members of the VFW, local politicians, and the mayor of Canonsburg.