The Canton of Vesoul-2 (before March 2015: Vesoul-Est) is a French administrative division, in the arrondissement of Vesoul, in Haute-Saône département (Bourgogne-Franche-Comté région).

It consists of the eastern part of the commune of Vesoul and its eastern suburbs.

[2] It has 16,072 inhabitants as of 2017.

[3] The canton of Vesoul-2 is composed of 13 communes:[2]