Cantua Creek is located 11 miles (18 km) south-southwest of Tranquillity,[6] at an elevation of 295 feet (90 m).

[5] According to the United States Census Bureau, the CDP has a total area of 3.8 square miles (9.8 km2), all of it land.

[7] The community of Cantua Creek is located near Cantua Creek, a tributary of the Fresno Slough that flows down from the Coast Range to the west toward the Fresno Slough.

That creek originally, Arroyo de Cantua, was a stopping place on the El Camino Viejo.

The hideout of Joaquin Murrieta was located in the vicinity of this creek in the mountains to the west of this community.

[6] The 2010 United States Census[24] reported that Cantua Creek had a population of 466.

6 households (5.3%) were made up of individuals, and 1 (0.9%) had someone living alone who was 65 years of age or older.

2.8% of all households were made up of individuals, and none had someone living alone who was 65 years of age or older.