John S. Pope Farm is a historic tobacco farm complex located near Cedar Grove, Orange County, North Carolina.

The farmhouse was built between 1870 and 1874, and is a two-story, frame I-house with a one-story ell.

It sits on a stone pier foundation, has a triple gable roof, and features stone gable end chimneys.

Also on the property are the contributing well house (c. 1920), washhouse (c. 1875, 1930s), garage / smokehouse (c. 1900, c. 1920), flower house (c. 1900), two corn cribs (c. 1900, c. 1930), feed barn (c. 1900), tobacco ordering/stripping house (c. 1935), two curing barns (c. 1955), stick shed (c. 1950), five tobacco barns (c. 1875-1955), a spring-fed well (c. 1909), workshop (c. 1960), a small log building (c. 1880), two wood sheds (c. 1920, c. 1950), and the surrounding agricultural landscape.

This article about a property in Orange County, North Carolina on the National Register of Historic Places is a stub.