Its wide range extends north to Québec and Nova Scotia, south to Georgia and Alabama, and west to Wisconsin.

[8] It is known to occur in the following provinces and states:[3][10] Its distribution is centered in the Great Lakes region of North America.

[11] It is found in moist woodlands usually in edge habitats and blooms from April to June.

[12] The West Virginia white butterfly (Pieris virginiensis) lays its eggs on this plant as well as C. laciniata.

[1] The ground root is mixed with vinegar by the Algonquin people of Quebec and used as a relish.

[19] The Delaware Nation of Oklahoma use a compound containing the root as a stomach remedy, for scrofula, and for venereal disease.

[28] The Cherokee parboil and rinse the stems and leaves, add hot grease, salt & water & boiled them until they are soft as potherbs.