The Quins were formed in 1935,[1] and progressed in the 1990s from 'parks' football into the Welsh League, via the FAW Pyramid system.

A second relegation followed in 2006–07, and the club's prospects of returning to the Premier in the short term looked slim.

[3] With the demolition of the old Cardiff Athletics Stadium in 2007 Grange Quins lost their home ground.

In 2014–15 the Cardiff Grange Harlequins resigned from the Welsh League towards the end of the season[1] and their record was expunged.

The club was reformed in 2020 as Grangetown Harlequins,[5] playing in the Cardiff & District League Division Three for the 2021–22 season, but withdrew mid-season.