Cardiknox signed with Warner Bros. Records in 2015 and released their debut album Portrait in March 2016; they also reached number 13 on the Billboard Spotify Viral 50 chart with the song "Wild Child".

The musical was a success, but the duo made the decision to leave it behind and form a band in 2013.

[6] Throughout 2015, Cardiknox played at big festivals in the United States, Canada, and Europe, including Lollapalooza, Firefly, Sasquatch, Reading, Leeds, and Pukkelpop.

[2] After six months spent at Henson Recording Studios in Hollywood,[1] the album Portrait was released on March 11, 2016.

[11] On December 7, 2018, the band released "Back in L.A." and announced on social media that it was the end of their work together.

The duo cites Peter Gabriel, Cyndi Lauper, Madonna, and Drake as influences.

[16] Reviewing the appearance of Cardiknox at CMJ Music Marathon, The Guardian described their sound as "glittering, skittering electro-pop (...) with songs in the vein of bands like Chvrches and The Naked and Famous.

"[17] Commenting their single Wasted Youth, MTV said Angle sounded "like a mix between Icona Pop and Sky Ferreira with an electro-pop/dub jones.