The school is named after John Francis O'Hara who was Roman Catholic Archbishop of Philadelphia from 1951 to 1960.

It is located in Marple Township, Pennsylvania, and was officially opened for the first time in 1963.

[3] The position of president was established in 1993 for all archdiocesan high schools.

The president is responsible for financial operations, facilities issues, fund raising, alumni relations, and external affairs.

Since the establishment of the position of President in 1993, the principal's duties are concentrated on the day-to-day operations of the school.