Buchholz had been married to Christiane Wilhelmine Kunsemüller, the daughter of a doctor from Wittstock, since 9 September 1820.
His son Carl Friedrich Buchholz (7 July 1821 in Berlin – 17 February 1885 idem) first learned from his father and worked as a journeyman for Aristide Cavaillé-Coll in Paris around 1847/48.
Buchholz was appointed "Academic Artist" in 1853 by the Academy of Arts (or the Prussian government ?).
After his death in 1884, his son Carl Friedrich Buchholz continued to run the workshop for a short time and died himself about six months later.
The action was made with waveboards, modelled on those of Joachim Wagner and Ernst Julius Marx.
Buchholz usually had architects such as Karl Friedrich Schinkel design the fronts for larger organs.
Buchholz influenced a number of young organ builders who went on to work independently in various regions.
All of Buchholz's organs have purely mechanical slider chests with the wedge loops he invented.