In 2018 Trueman left Westminster and became a professor at Grove City College in their Department of Biblical and Religious Studies.

[3][4] Among Trueman's books are John Owen: Reformed Catholic, Renaissance Man,[5]The Creedal Imperative,[6] Fools Rush in Where Monkeys Fear to Tread: Taking Aim at Everyone,[7] and Republocrat: Confessions of a Liberal Conservative.

[8] In 2020, Trueman published what is probably his most popular and widely read[9] book, The Rise and Triumph of the Modern Self: Cultural Amnesia, Expressive Individualism, and the Road to Sexual Revolution.

[11] He contributes to First Things (Journal of Religion and Public Life)[12] blogs regularly at Reformation21[13] and co-hosts the Mortification of Spin[14] podcast.

Trueman is an ordained minister in the Orthodox Presbyterian Church, and was the pastor of Cornerstone OPC in Ambler, Pennsylvania.