[1] He made his senior debut with the C-team on 24 August 2019, starting in a 3–0 Tercera División away win against CF Recambios Colón.
[2] Carlo Adriano scored his first senior goal on 1 September 2019, netting the game's only in a home success over CD Olímpic de Xàtiva.
[4] Ahead of the 2020–21 season, Carlo Adriano was assigned to the reserves in Segunda División B, and made his debut for the side on 18 October 2020 by starting in a 0–1 loss at SCR Peña Deportiva.
[7][8] Carlo Adriano made his professional – and La Liga – debut on 3 January 2022, replacing fellow youth graduate Manu Trigueros in a 5–0 home routing of Levante UD.
[9] He scored his first professional goal on 12 October, netting the B's first in a 2–2 Segunda División home draw against SD Ponferradina.