[1] Based in Chicago, Murillo is a professor and head of the Playwriting program at the Theatre School at DePaul University.

with Stage Left and Cor Theatre in Chicago[3] as well as the world premiere of Honey Girls by Grace Grindell at The Theatre School of DePaul University,[4] where he also staged works by Sam Shepard, Jason Grote, Nilo Cruz, David Edgar, Ike Holter, and others.

The radical nature of Murillo's structural choices fully destabilizes both the reading experience and any assumption an audience might hold regarding the constitution of a play."

[11] Your Name Will Follow You Home (2015) Your Name Will Follow You Home, originally commissioned by Steppenwolf Theatre Company,[12] received its world premiere at New York City's Repertorio Español as Spanish language version titled Su Nombre Sera Su Sombra Para Siempre, translated by Caridad Svich.

[14] Dark Play or Stories for Boys received its world premiere at the Humana Festival in 2007, produced by the Actors Theatre of Louisville.

— Scotty Zacher, Chicago Theater Beat[17] Murillo studied toward a BFA in acting at Syracuse University but did not complete it.