Don Carlos Manuel O'Donnell y Álvarez de Abreu, 2nd Duke of Tetuan Grandee of Spain, 9th Marquis of Altamira and 2nd Count of Lucena (1 June 1834, in Valencia – 9 February 1903, in Madrid) was a Spanish noble and politician who served four times as Minister of Foreign Affairs, the name which then received the Spanish Foreign Minister.

He was also Mayordomo mayor to King Amadeo I. O'Donnell was born on 1 June 1834 in Valencia.

[1] The Duke was the son of Carlos María O'Donnell y Joris, eldest brother of General Leopoldo O'Donnell, 1st Duke of Tetuan (several times Prime Minister of Spain), and Maria del Mar Álvarez de Abreu y Rodríguez de Albuerne, 8th Marquesa of Altamira and the granddaughter of Don Manuel Rodriguez de Albuerne y Pérez de Tagle, 5th Marquis of Altamira.

During his tenure, he would attempt to push against the Monroe Doctrine in the face of the United States pressuring to grant autonomy for Spanish Cuba.

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