He is remembered for his raid on English soil, known as the Raid on Mount's Bay, in the context of the Brittany Campaign during the Anglo-Spanish War 1585–1604.

Amésquita commanded three companies and four galleys (named Capitana, Patrona, Peregrina and Bazana).

They disembarked at Penmarch on 26 July, and in Mount's Bay (Cornwall) on 2 August.

After burning the town of Mousehole, Amésquita and his men embarked on their galleys and sailed for two miles, after which they disembarked again, conquered and burned the fort of Penzance down, Newlyn, and Penzance.

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