The ship's maiden voyage embarked on May 1, 2016 from Trieste, Italy on a 13-day Europe Cruise that ended in Barcelona, Spain.

[8] On August 28, 2016, Carnival Vista's wake caused extensive damage to the tourist harbor of Marina del Nettuno, near Messina, Italy.

[18][19] From May to October 2016, Carnival Vista operated an inaugural season in the Mediterranean before repositioning to New York to offer a pair of cruises.

[20] She offered six, seven, and eight day Caribbean cruises with ports of call such as Ocho Rios, Montego Bay, Grand Cayman, Cozumel, Aruba, Curaçao, and Bonaire.

[citation needed] In July 2019, when the vessel was underway to its call in Galveston, it temporarily lost power in the middle of the Gulf of Mexico.