[citation needed] Márquez left Colombia in 1986 for Spain to study drama at the Escuela de Arte Dramático in Barcelona.
In 2004, Carolina Márquez had an international hit with "The Killer's Song" based on the music of "Twisted Nerve" by composer G. Hermann, when it was used in the soundtrack of the film Kill Bill by Quentin Tarantino.
In 2005, a follow-up "The Killer's Song Vol II" was released with remixes by well-known Euro DJs including one by The Disco Boys, a German electronic duo act.
A follow-up single "Pleasure Ground" was also a hit in Italy in addition to some international success with Márquez heavily touring Europe.
In 2012, she released "Weekend (Wicked Wow)" that was credited as Carolina Márquez vs Jay Kay and featuring Lil Wayne & Glasses Malone.