[1] White was also an active clubwoman, and was involved in literary societies and women's suffrage, and worked with organizations that helped the poor obtain medical services.

Thomas Earle was a successful Philadelphia lawyer who was devoted to the abolitionist cause and often represented both free and fugitive African Americans.

She wrote and published several travel guides, short stories, and novels, including A Holiday in Spain and Norway, Love in the Tropics: A Romance of the South Seas, and An Ocean Mystery.

After her conversion to Catholicism, she became president of the St. Vincent’s Aid Society, an organization that donated medical services and supplies to poor and orphaned children.

In fact, White firmly believed that one social injustice could lead to another, as evidenced with her involvement with the Women’s Christian Temperance Union.

She said, “Ought we not then, in our desire to ameliorate the sufferings of our dumb friends, to add our efforts to those who are laboring for a reform in this manner?” The WPSPCA built water fountains in cities all over the country to provide men and animals a place to drink besides the local bar.

In the summer of 1866, Caroline Earle White visited Henry Bergh in New York; she was seeking advice on how to begin a Philadelphia chapter of the SPCA.

White drafted a petition calling for the creation of a Philadelphia chapter of SPCA, and secured dozens of signatures and pledges of financial support.

White urged her members to boycott cruel carriage horse companies and to place malicious drivers under citizens arrest.

Operating out of Bensalem, PA, the Women's Humane Society has managed to save, heal, and find homes for animals in the Delaware Valley for over 145 years.

In 1871, physician S. Weir Mitchell wrote a letter to White requesting that the WPSPCA relinquish unwanted dogs from their shelter to his research hospital, for experimental purposes.

[10] Frances Power Cobbe, British antivivisectionist and feminist, advised White to create an organization that would address the use of animals in testing, research and education.

[2] The organization utilized the support of celebrities, politicians, and writers, including Mark Twain, to validate the issue and raise awareness.

Volunteers passed out millions of leaflets addressing the topics of pets stolen for research and the deplorable housing provided for lab animals.

[3] White's niece, Philadelphia poet Florence Earle Coates, reflected on her aunt: "She was a great woman with the heart of a little child.