Bush (CVN-77), the strike group's current flagship, with Carrier Air Wing Seven embarked on board, as well as the Ticonderoga-class cruiser Leyte Gulf, and four ships of Destroyer Squadron 26.

Carrier Strike Group 10's lineage can be traced to Destroyer Flotilla 2, which was established during the First World War at Naval Station Newport, Rhode Island.

[15] In 1993, following a fleet reorganization, the group staff went aboard a new flagship, the new Nimitz class aircraft carrier USS George Washington (CVN-73).

[42] Despite plans to cross the equator and visited South Africa, diplomatic issues caused the strike group to transit the Suez Canal, stopping in Portsmouth, England, prior to returning to the United States on 19 April 2005.

[48][50] Following humanitarian assistance and disaster response operations in the aftermath of Hurricane Katrina in September 2005, Truman underwent an extended yard period at the Norfolk Naval Shipyard in Portsmouth, Virginia.

This included flying almost 14,000 combat hours and expended 77,500 pounds of ordnance during 228 troops-in-contact events, as well as providing defense to the Iraqi oil platforms.

Finally, Destroyer Squadron 26 provided security patrols in the northern Persian Gulf to protect the vital Khor Al-Amaya and Al-Basra oil terminals from possible terrorist attacks.

[64] Detachments from helicopter squadron HSL-44 based on board the destroyers Oscar Austin and Winston S. Churchill flew a combined 1,875 hours in support of anti-piracy operations, multinational training events, and counter-smuggling missions in the Gulf of Aden and Indian Ocean.

[66] On 5 July 2010, the guided-missile frigate Elrod assisted 16 stranded Pakistani fishermen (pictured) whose boat had taken on water and sank two days earlier.

After being spotted floating adrift in a life raft by a Task Force 57 Lockheed P-3 Orion, the stranded crew was recovered by the Elrod's rigid-hulled inflatable boat before being transferred to the Pakistani Navy frigate PNS Babur on 6 July 2010.

[67] On 18 November 2010, guided-missile destroyer Oscar Austin located and provided assistance to two Iranian mariners who were spotted floating in a life raft in the Persian Gulf.

[68] On 15 November 2010, four Sikorsky CH-53E Super Stallion helicopters from squadron VMM-266 landed and re-fueled on board the carrier Harry S. Truman following operations in Afghanistan and Pakistan.

These VMM-266 helicopters part of the 26th Marine Expeditionary Unit, and they were returning to the amphibious assault ship Kearsarge after completing humanitarian relief efforts in Pakistan.

[75][76] Between 31 July and 2 August 2011, Destroyer Squadron 26 participated in a passing exercise with Japan Maritime Self Defense Force ships off the east coast of the United States.

[77][78] Passing exercises are designed to provide realistic training environments that closely replicates the operational challenges routinely encountered around the world.

[77][78] Between 19 and 29 June 2012, the group staff participated in War of 1812 Commemoration Fleet Exercise, or 1812 FleetEx, with Rear Admiral Herman Shelanski embarked on the helicopter carrier Wasp.

[79] On 7 July 2012, Harry S. Truman departed Norfolk Naval Shipyard, Virginia, for sea trials (pictured) following its 16-month-long docking planned incremental availability overhaul.

[83] On 14 January 2013, the strike group began its Composite Training Unit Exercise in order to undertake a surge deployment to the U.S. Fifth Fleet, two months ahead of its previously scheduled departure date.

[84] One unit of Carrier Strike Group Ten not part of this surge deployment was the guided-missile cruiser San Jacinto which was undergoing repairs following a collision with the nuclear-powered attack submarine Montpelier on 13 October 2012 during training exercises off the coast of Florida.

It was also announced that the Ticonderoga-class guided-missile cruiser Gettysburg and the German frigate Hamburg would join the strike group for its upcoming 2013 deployment.

[88] On 22 July 2013, Carrier Strike Group Ten departed Norfolk Naval Base, Virginia, for its 2013 deployment to the Persian Gulf and Indian Ocean.

[93] Both U.S. Navy carrier strike groups remained in the north Arabian Sea area pending potential military action against Syria amid allegations that the regime of Syrian president Bashar al-Assad used chemical weapons during the ongoing Syrian civil war, including the gas attacks that occurred on 21 August 2013.

The two mariners were brought on board San Jacinto for medical examination prior to transferring them to the Yemen Coast Guard on 17 November 2013.

[106] Subsequently, Harry S. Truman entered the Norfolk Naval Shipyard, Virginia, to begin its yard maintenance period on 5 November 2014.

[104] On 27 May 2015, the Harry S. Truman completed five days of sea trials following its six-month condensed incremental availability (CIA) maintenance period.

Over 1,340 pallets of ordnance weighing estimated 3,900,000 lb (1,800,000 kg) were transferred to the Truman in preparation for the upcoming work-up exercise cycles for 2015 deployment of Carrier Strike Group Ten.

The Navy's involvement in the humanitarian assistance operations was led by the Federal Emergency Management Agency (FEMA) in conjunction with the Department of Defense.

[122] Beginning in Fiscal Year 2015, the Optimized Fleet Response Plan aligns carrier strike groups to a 36-month training and deployment cycle.

All required maintenance, training, evaluations, plus a single eight-month overseas deployment, are scheduled throughout this 36-month cycle in order to reduce costs while increasing overall fleet readiness.

[7] USNI News reported that CSG-10 is most likely set to relieve Carrier Strike Group 8 (CSG-8) and its flagship, the USS Harry S. Truman (CVN-75), in the Mediterranean Sea.