Carthage Courthouse Square Historic District is a national historic district located at Carthage, Jasper County, Missouri.

It developed in the late-19th and early-20th centuries and includes representative examples of Italianate and Romanesque Revival style architecture.

Located in the district is the separately listed Jasper County Courthouse.

Other notable buildings include the Bank of Carthage, Ben Franklin Store (1920s), Farmers and Drovers Bank / Miller Clothing Company (1875, 1908), Belk-Simpson Building (pre-1884), Carthage Water & Electric Co. (pre-1884), Snyder Building (1901), Drake Hotel (1920), Fire Department (1883), Leggett and Platt (1920), McNerney Block (1905), and Carthage National Bank.

This article about a property in Jasper County, Missouri on the National Register of Historic Places is a stub.