Cascabel is a rural community in Cochise County, Arizona, United States.

It is located at 32.291N / 110.378W, on the banks of the San Pedro River, east of Tucson and about 37 km north-northwest of Benson.

The name Cascabel derives from Spanish for "rattle", because an early settler killed a large rattlesnake here.

The post office was started by Alex Herron, a small ranch and store owner, in 1916.

When deciding what to name the Cascabel post office, Herron, while on the way to Benson, met a Mexican man with a dead rattlesnake.