Caseville was settled by European Americans beginning with settler Reuben Dodge in 1836.

Later, it was known as Port Elizabeth and Elizabethtown for the wife of William Rattle, who was agent for major landowner Leonard Case.

[5] The town developed through lumbering, with timber shipped via the lake to markets.

In 1856, Francis Crawford purchased 20 thousand acres from Case around the community.

[4] A detachment effort to return three sections of the city back to the Caseville Township was underway in 2016.

42.9% of all households were made up of individuals, and 20.7% had someone living alone who was 65 years of age or older.

39.4% of all households were made up of individuals, and 23.4% had someone living alone who was 65 years of age or older.

The annual Cheeseburger in Caseville festival is held to end the summer with concerts and family activities.

Nearby Sleeper State Park has campgrounds and a variety of trails and habitats.