In the second-half of the 19th century, there was an expansion is the transportation system, both on the high seas and on land, to protect this routes lighthouses and casas de camineros (or road worker's homes), respectively, were built.

[1]: 14–18 The Casilla del Caminero, as the oldest structure in the campus is popularly called, suffered damage from the San Fermín earthquake, which occurred on 11 October 1918.

Two years later, in 1920, the structure was repaired by installing "a system of internal rods screwed into exterior plates which tied and stabilized the walls."

[1]: 20–23 [2] In the mid 1950s, the road workers program is shutdown[1]: 7–11  and the structure comes to be an office for the Department of Transportation and Public Works (DTOP).

The campus had "an indispensable requirement...that if at any moment the Campus...did not have use for this property, the title would revert to the [DTOP]..."[5] In the first half of the decade of the 1990s, the Post Road, later to be named the Alfonso Valdés Cobián Boulevard (PR-2R), was expanded, and the structure was moved back from the road, adding the base cement and the transfer of the title of the property was completed.