Born in Llano, Texas, United States, in the late 1940s, Webb began playing guitar at 14 and later became involved with the psychedelic scene in San Antonio.

She became a member of the Children, a psychedelic group that was part of Lelan Rogers' stable of artists, appearing on their 1968 Rebirth album and several singles.

Sloan"), Nick Drake ("Time Has Told Me"), Townes Van Zandt ("If I Needed You"), and Phil Ochs ("Jim Dean of Indiana").

Webb's version of the Rolling Stones track "Tell Me," from her 1990 album Conversations at Dawn, was included on the Connoisseur Collection's Jagger/Richard Songbook CD.

In 2024, a selection of "Works in Progress over the years" with Craig Leon entitled The Ghost That Walks Behind Me was issued digitally via the Bandcamp platform.