It is located in the town centre of Reading, in the English county of Berkshire, and is a few yards from the similarly named, but much older Minster Church of St Mary the Virgin.

In 1798, there was a disagreement between the Bishop and the congregation of St Giles' Church in nearby Southampton Street.

Many of the congregation left and founded a new chapel in Castle Street, on the site of Reading's old gaol.

The frontage is rendered in stucco while the capitals of the portico are probably formed of Coade stone.

There is a modillion cornice to the coved central ceiling and a small projecting chancel with a bay for the mid-19th-century organ.