The character was played by Tracy Scoggins in Lois & Clark: The New Adventures of Superman and Calista Flockhart in the Arrowverse television series Supergirl.

Created by writer Marv Wolfman and artist Jerry Ordway, Cat Grant first appeared in The Adventures of Superman #424 (January 1987) as a gossip columnist for the Daily Planet.

There are rumors that she got the position thanks to a relationship with Morgan's father Vincent Edge, her new boss who sexually harasses her constantly.

When the Justice League of America unveils a new roster, various members of the press are invited to the JLA Watchtower in order to cover the story.

Cat receives an invitation, but is apparently incapacitated offscreen by Catwoman, who dresses up in her clothes to rob the Watchtower (although her presence subsequently proves important in helping the League defeat new villain Prometheus).

During Lex Luthor's tenure as President of the United States of America, Cat serves as White House Press Secretary.

[6] Cat Grant holds a grudge against Supergirl because of her lack of respect and careless handling of a metahuman fight that left her slightly wounded.

Cat starts a slander campaign against Supergirl in the pages of the Daily Planet, turning a large number of the Metropolis population against her.

[10] Afterward, Cat and Supergirl eventually visit Arkham Asylum, where they find Toyman in the cell where Adam was murdered.

[11] Dollmaker eventually reveals himself to be the abandoned son of Winslow, who has been kidnapping children and using macabre experiments in order to turn them into slaves.

With her gag temporarily removed, Cat is able to call Supergirl for help, and the two are able to defeat Dollmaker and free the children he had enslaved.

[12] The 2009–10 miniseries Superman: Secret Origin establishes that Cat, in post-Infinite Crisis continuity, is already on the staff of the Daily Planet when Clark Kent began working at the newspaper.

In DC Rebirth, taking inspiration from Supergirl, Cat was re-introduced as the CEO of CatCo Worldwide Media in National City.

Cat's personality has undergone a noticeable change, becoming far more arrogant, commanding, and snarky than previously seen in the New 52 and often comes off as ruthless, unapologetic, unsympathetic, and uncompromising, similar to the iteration from the television series Supergirl.

However, she seemed to be a good judge of character, able to see the potential in many people including Kara Danvers and Ben Rubel.