Caterina di Guisa is an opera in two acts by Carlo Coccia to a libretto by Felice Romani based on the 1829 play Henry III and His Courts by Alexandre Dumas.

Caterina di Guisa premiered on 14 February 1833 at the Teatro alla Scala in Milan[1] with triumphal success.

[2] In modern times, Caterina di Guisa was revived at the Teatro Gabriello Chiabrera [it] in Savona on 30 October 1990.

San Megrino courts the Duchess Caterina: he has fallen in love with her, although she is the wife of his enemy, the Duke of Guise.

Later the Duke encounters San Megrino and they accuse each other of plotting against the King (duet: "Pera chi vuol turbarla" / "May die who wants to break the peace").

Caterina appears, worried for losing her handkerchief, then Arturo reads some love verses of the French poet Pierre de Ronsard ("Deh!

Later the Duke forces Caterina to admit to have been courted by San Megrino (duet: "E infierir così potete / Ah!

Arturo delivers the letter of Caterina and San Megrino, happy, tells him to go back to the Duchess and to reassure her.

Then San Megrino, with the help of Arturo that provides him with a rope, flees from the window, just in time to avoid the Duke, who enters knocking down the door ("Ov'è desso?"