[2] During the middle ages the town was a best equipped fortress ("fortissima arx nucerina") ramparted by the Lombards in defense of the Duchy of Spoleto against the Byzantines who controlled Gualdo Tadino and Gubbio.

[4] In July 1487 were buried in the church the relics of St. Raynald, patron saint of the city, whose remains rest today under the high altar.

Of the 11th century construction remains the Romanesque portal decorated with vine sheets and animals on the left side of the building.

[4][2] The facade, which is rather incongruously choked by the Campanaccio, the tower which is the only remain of the Trinci's castle, has stone decorations[4] and a central Oculus.

[4] Internally, the building has a single large nave with side chapels and a semicircular apse,[4] and is richly decorated with stuccoes.

[5] Many works once in the church have been moved to in municipal Pinacotheca in the church of San Francesco: among them, the altarpiece Adoration of the Child with angels, Saints, Coronation of Virgin Mary, Apostles painted in 1483 from Niccolò di Liberatore detto l'Alunno, and the Meeting of Saint Anne and Joachim at the Porta Aurea, Immaculate Conception, Saints painted between the centuries XV and XVI from Matteo di Pietro da Gualdo, which was previously placed in the chapel of the Immaculate.