The Cathedral of Saints Constantine and Helen is a historical Greek Orthodox Church in Johannesburg, designed by architect Hermann Kallenbach and built in 1912.

The white walled church was designed by Hermann Kallenbach who was a close friend and admirer of Mahatma Gandhi.

The church was required by the growing population of Greeks who had moved to Yeoville and Berea in the 19th century.

[3] Kallenbach created a church in the Byzantine style[3] in 1912 for the Greek community with a number of different roof levels which were not designed to be at the same angle.

The church is a South African Heritage Resources Agency (SAHRA) protected site.