Catherine Malfitano (born April 18, 1948) is an American operatic soprano and opera director.

Malfitano made her professional singing debut in 1972 at the Central City Opera in the role of Nannetta in Verdi's Falstaff.

She performed in 1974 as Susanna in a new production of Mozart's Le nozze di Figaro at the Holland Festival, and in 1976 as Servilia in a new production of Mozart's La Clemenza di Tito at the Salzburg Festival.

The opera was broadcast live from the actual Roman settings and viewed worldwide.

Throughout her career, Malfitano has championed the music of American composers, including Carlisle Floyd, William Bolcom, Conrad Susa and Thomas Pasatieri.