Catthorpe is a village and civil parish in the Harborough district of Leicestershire, England.

It is located beside the River Avon and close to the A5 road, and hence close to the tripoint at Dow Bridge formed by Leicestershire, Northamptonshire and Warwickshire; the nearest towns are Rugby, in Warwickshire around 4 miles (6.4 km) to the southwest, and Lutterworth around 4 miles (6.4 km) to the north.

'Cat' was probably added after Isabel le Cat and Simon Mallore donated the land to Leicester Abbey.

Between 2014 and 2016 the interchange was the subject of a major redesign to reduce the congestion and improve safety by providing free-flowing links and removing direct access from the local road network.

There is a village pub called the Cherry Tree and a farm shop and restaurant, both located on Main Street.