Covering 267 km2 (103 sq mi), it is the largest of the nation's seven districts in terms of area.

It is divided into the two statistical subdistricts São João dos Angolares and Malanza.

Much of the district lies within Parque Natural Obô de São Tomé.

[4] The most notable natural landmark is the volcanic vent Pico Cão Grande.

The main settlement is the town São João dos Angolares.